Showing posts from August, 2011

Synthetic compound SRT1720 helps obese mice live longer

Researchers are testing the effect of a synthetic resveratrol stimulator, known as SRT1720 to see if it might treat human diseases, reverse metabolic syndrome and help people live longer. In mouse studies, the compound did just that.

The compound has been suggested to have anti-aging properties from past studies.
SRT1720 activates a class of enzymes known as sirtuins, which are associated with the same positive health effects as calorie restriction.
In obese mice, scientists found improved liver, heart and pancreas function, compared to mice not given the patented compound.
The study is a collaborative effort of the National Institute on aging (NIA) and the drug company Sirtris, a GlaxoSmithKline company, and is published in the August 18, 2011, issue of Scientific Reports.
Drug suppresses gene pathway linked to aging

“This study has interesting implications for research on the biology of aging. It demonstrates that years of healthy life can be extended in an animal model of diet-induced o…