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Showing posts from April, 2010

Almost 16,000 COVID-19 patients get hydroxychloroquine and here's what happened

In a new study from Brigham and Women’s hospital, nearly 16,000 patient outcomes were analyzed that were diagnosed with COVID-19 and received the drug hydroxychloroquine.
Instead of improving, patients were four times more likely to experience dangerous heart irregularity, compared to those not teated with the antimalarial drug.
Patients in the study that were given hydroxychloroquine were also more likely to die.
The study is recently published in the medical journal The Lancet  and is the most recent to address a hot topic about whether the medication, which is also prescribed to treat autoimmune disorders, should be  used to treat COVID-19.
Mandeep R. Mehra, a corresponding study author and executive director of the Brigham’s Center for Advanced Heart  Disease said the drug, or any regimen including a chloroquine,  did not help “no matter which way you examine the data.”
Patients from six continents included 
The researchers looked at data from 671 hospitals that included six continents …

HPV test more sensitive than PAP smear for detecting cervical cancer lesions

Findings from researchers, published in the British Medical Journal, reveal that HPV (human papillomavirus) testing is more sensitive for detecting precancerous lesions that can lead cervical cancer, compared to PAP smear. Dr Ahti Anttila at the Finnish Cancer Registry who led research says the findings that HPV testing is more sensitive than PAP smear are important for cervical cancer prevention.

In a trial of 58,282 women aged 30-60, HPV testing detected more precancerous cells than routine cytology exam performed with a traditional PAP smear.

Women were studied between 2003 and 2008 in Finland and randomly assigned to a routine PAP smear or an HPV test. For women with positive HPV testing, further screening was conducted. Traditional cancer screening using a PAP smear was inferior for detecting cervical lesions that could lead to cancer compared to HPV testing.

Over a period of five years the women were tracked. The number of pre cancerous cells (cervical intraepithelial neoplasi…

Overdiagnosis of cancer focus of review

An analysis of cancer diagnosis in the past 30 years related to mortality and screening for the disease shows that overdiagnosis of cancer should become a focus of the medical community. Researchers H. Gilbert Welch, M.D. and William Black, M.D., of the Dept. of Veterans Affairs Medical Center, White River Junction, Vt. and the Dartmouth-Hitchcock Medical Center conducted a review, finding that many cancers are diagnosed that would never require treatment.

Following a systematic review, the researchers learned that though cancer diagnosis has increased, there has been no association with mortality to account for the rising numbers. Overdiagnosis of cancer occurs from sophisticated screening tools that the researchers say could cause harm to some individuals.

The study authors write, "Whereas early detection may well help some, it undoubtedly hurts others. Often the decision about whether or not to pursue early cancer detection involves a delicate balance between benefits and harms……

Women Fail to Recognize Osteoporosis Risk Shown in Study

A study shows that women questioned in 10 countries failed to recognize risk for fracture from osteoporosis. Results of the Global Longitudinal Study of Osteoporosis in Women (GLOW) show that among 60,000 postmenopausal women studied, only 43 percent perceived themselves at risk for fracture from osteoporosis compared to women not diagnosed with disease.

Thirty three percent of women already diagnosed with osteoporosis also failed to recognize their risk factors for fracture - a finding that researchers say is a public health concern.

"We've found that many women aren't making the connection between their risk factors and the serious consequences of fractures," said the lead author of the paper, Ethel Siris, MD, GLOW investigator and Director of the Toni Stabile Osteoporosis Center of the Columbia University Medical Center, New York-Presbyterian Hospital. "Without a clear understanding of their risks, women cannot begin to protect themselves from fracture."